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Chapter3_Comorbid_Supplementary_tables.xlsx (2.61 MB)

Chapter 3 Supplementary tables

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posted on 2022-01-31, 22:47 authored by Sophie FarrowSophie Farrow

This repository contains the supplementary tables for Chapter 3: Network-based identification of pleiotropic genes for Parkinson's disease and Type II Diabetes


Supplementary Table 1: GWAS SNP sets used for analyses - T2D and PD

Supplementary Table 2: PD GWAS: Sig. eQTLS CoDeS3D output - CNS tissues only

Supplementary Table 3: PD GWAS: Sig. eQTLS CoDeS3D output - All non-CNS tissues

Supplementary Table 4: T2D GWAS: Sig. eQTLS CoDeS3D output - CNS tissues only

Supplementary Table 5: T2D GWAS: Sig. eQTLS CoDeS3D output - All non-CNS tissues

Supplementary Table 6: gProfiler pathway analysis of all PD genes - non-CNS tissues

Supplementary Table 7: gProfiler pathway analysis of all T2D genes - non-CNS tissues

Supplementary Table 8: gProfiler pathway combined analysis - CNS tissues only

Supplementary Table 9: gProfiler pathway combined analysis - All non-CNS tissues

Supplementary Table 10: T2D and PD eQTLs converge on 23 shared target genes in CNS tissues

Supplementary Table 11: Literature search of 23 pleiotropic target genes in brain

Supplementary Table 12: T2D and PD eQTLs converge on 96 pleiotropic target genes in non-CNS tissues

Supplementary Table 13: gProfiler pathway analysis of the 96 pleiotropic target genes

Supplementary Table 14: Literature search of 96 pleiotropic target genes in non-CNS tissues

Supplementary Table 15: DGIdb druggability analysis of the 96 non-CNS pleiotropic target genes



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