Nicholas Knowlton

Publications

  • Methods for inflammatory disease management
  • Methods, System, And Medium For Associating Rheumatoid Arthritis Subjects With Cardiovascular Disease
  • Apolipoprotein B--containing lipoprotein subclasses as risk factors for cardiovascular disease in patients with rheumatoid arthritis
  • Methods for diagnosis and prognosis of inflammatory bowel disease using cytokine profiles
  • Biomarkers and methods for measuring and monitoring inflammatory disease activity
  • Cytokine profiles as methods for diagnosis and prognosis of irritable bowel syndrome
  • Gene Expression-Based Differential Diagnostic Model for Rheumatoid Arthritis
  • In silico models of leukocyte gene expression data in children with polyarticular JIA show hub-and-node structures typical of scale-free networks: Implications for pathogenesis and treatment
  • Estrogen receptor signaling promotes langerin+ dendritic cell differentiation by increasing expression of the transcription factor IRF4 (87.1)
  • Methods, System, and Medium for Associating Rheumatoid Arthritis Subjects with Cardiovascular Disease
  • Gene expression profiling in juvenile dermatomyositis suggests complex interactions between 2 innate and adaptive immunity
  • Leveraging Cancer Genomics to Answer Clinically Motivated Questions: A Statistical Perspective
  • Development of a multivariate disease activity test in rheumatoid arthritis
  • Mlcroarray analysis In TNBS colitis
  • A Predictor of Early Disease Recurrence in Patients With Breast Cancer Using a Cell-free RNA and Protein Liquid Biopsy
  • Validation of the power model of ovarian non-growing follicle depletion associated with aging
  • Methods For Inflammatory Disease Management
  • The NETwork! Registry Suggests Increasing Incidence in a National Study of Neuroendocrine Cancer in New Zealand (NZ)
  • Novel Biomarkers for the Prediction of Subclinical Coronary Artery Atherosclerosis in Patients with Rheumatoid Arthritis
  • Three distinct genomic landscapes define clinical outcome of pancreatic neuroendocrine tumours (pNETs)
  • Brief FASD prevention intervention: physicians’ skills demonstrated in a clinical trial in Russia
  • lymphatic, and inflammatory cell responses of the bladder to intravesical BCG treatment
  • Neutrophil regulation of adaptive immunity: an in vitro model identifies hubs and nodes with similarities to those seen in polyarticular JIA
  • Defining remission in polyarticular JIA: A systems biology approach
  • N-Methyl-D-Aspartate Receptor Hypofunction in Meg-01 Cells Reveals a Role for Intracellular Calcium Homeostasis in Balancing Megakaryocytic-Erythroid Differentiation
  • Breast cancer patient prognosis is determined by the interplay between TP53 mutation and alternative transcript expression: Insights from TP53 long amplicon digital PCR assays
  • Apolipoprotein B-containing lipoprotein subclasses as risk factors for cardiovascular disease in patients with rheumatoid arthritis
  • Brief FASD prevention intervention: Physicians' skills demonstrated in a clinical trial in Russia
  • Accessing a new dimension in TP53 biology: Multiplex long amplicon digital pcr to specifically detect and quantitate individual TP53 transcripts
  • Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma
  • Gene expression profiling of breast tumours from New Zealand patients
  • A new model of reproductive aging: the decline in ovarian non-growing follicle number from birth to menopause
  • Apolipoprotein-defined lipoprotein abnormalities in rheumatoid arthritis patients and their potential impact on cardiovascular disease
  • Gene expression profiling in neutrophils from children with polyarticular juvenile idiopathic arthritis
  • Oxidative stress and inflammation in renal patients and healthy subjects
  • Erroneous augmentation of multiplex assay measurements in patients with rheumatoid arthritis due to heterophilic binding by serum rheumatoid factor
  • A steroid metabolizing gene variant in a polyfactorial model improves risk prediction in a high incidence breast cancer population
  • Gene expression in systemic lupus erythematosus: bone marrow analysis differentiates active from inactive disease and reveals apoptosis and granulopoiesis signatures
  • Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients
  • Ablation of Stat3 by siRNA alters gene expression profiles in JEG-3 cells: a systems biology approach
  • Validation of the power model of ovarian nongrowing follicle depletion associated with aging in women
  • Tumor mutational burden is a determinant of immune-mediated survival in breast cancer
  • Disease-associated pathophysiologic structures in pediatric rheumatic diseases show characteristics of scale-free networks seen in physiologic systems: implications for pathogenesis and treatment
  • Correlation of ovarian reserve tests with histologically determined primordial follicle number
  • Idiopathic inflammatory myopathies, signified by distinctive peripheral cytokines, chemokines and the TNF family members B-cell activating factor and a proliferation inducing ligand
  • Development of a multi-biomarker disease activity test for rheumatoid arthritis
  • Recurrent loss of heterozygosity correlates with clinical outcome in pancreatic neuroendocrine cancer
  • Estrogen receptor signaling promotes dendritic cell differentiation by increasing expression of the transcription factor IRF4
  • The meaning of clinical remission in polyarticular juvenile idiopathic arthritis: gene expression profiling in peripheral blood mononuclear cells identifies distinct disease states
  • Neuropilin-VEGF signaling pathway acts as a key modulator of vascular, lymphatic, and inflammatory cell responses of the bladder to intravesical BCG treatment
  • Microarray Data Analysis Toolbox (MDAT): for normalization, adjustment and analysis of gene expression data
  • Hypervariable genes—experimental error or hidden dynamics
  • Comparative gene expression in the bone marrow vs peripheral blood in systemic lupus erythematosus (SLE): Bone marrow better separates active from inactive patients, and evidence for apoptosis and granulopoiesis signature
  • Biomarker analysis in native American Indian RA patients and their first degree relatives.
  • Identification of mouse retinal genes differentially regulated by dim and bright cyclic light rearing
  • The NETwork! Registry analysis supports the WHO 2017 classification in the first NET specific survival analysis for a complete population
  • Serum levels of anti-müllerian hormone and the ovarian antral follicle count are correlated with ovarian non-growing follicle number
  • P-684: The decline in ovarian non-growing follicle number from birth to menopause: A new model of reproductive aging
  • STEPWISE DEVELOPMENT OF A MULTI-PROTEIN BIOMARKER INDEX OF RA DISEASE ACTIVITY
  • P-0112: Microarray analysis in TNBS colitis: invivo effect of combination therapy with Nacetylcysteine and mesalamine on colonic tissue gene expression
  • STAT3 IS A TRANSCRIPTIONAL REPRESSOR IN TROPHOBLAST-LIKE JEG3 CELLS
  • Robust Estimation of Inter-chip Variability to Improve Microarray Sample Size Calculations
  • Disease activity and therapeutic response assessment in RA using multiplex cytokine profiling.
  • Polymorphisms of EPCR gene, anti-EPCR autoantibodies, sEPCR and cytokine levels in patients with SLE/APS.
  • A novel approach to identify prognostic biomarkers in serum from patients with chronic HCV infections
  • 152 DIFFERENTIAL GENE EXPRESSION IN THE BONE MARROW AND PERIPHERAL BLOOD OF SYSTEMIC LUPUS ERYTHEMATOSUS (SLE): BONE MARROW BETTER SEPARATES ACTIVE FROM INACTIVE LUPUS PATIENTS
  • Automated multiplexed cytokine bead assays
  • Hypervariable genes--experimental error or hidden dynamics.
  • A genome-scale assessment of peripheral blood B-cell molecular homeostasis in patients with rheumatoid arthritis
  • Statistical monitoring of weak spots for improvement of normalization and ratio estimates in microarrays
  • Connective molecular pathways of experimental bladder inflammation
  • Discriminators of mouse bladder response to intravesical Bacillus Calmette-Guerin (BCG)
  • Template-driven gene selection procedure
  • Analysis of the interaction of extracellular matrix and phenotype of bladder cancer cells
  • Multiplex serum cytokine monitoring as a prognostic tool in rheumatoid arthritis
  • Circulating cytokines in Norwegian patients with psoriatic arthritis determined by a multiplex cytokine array system
  • Mobile classification in microarray experiments
  • Distinct profiles of Sjögren's syndrome patients with ectopic salivary gland germinal centers revealed by serum cytokines and BAFF

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