Copy of Molly Ferguson - Mutant Huntingtin Aggregates and Neuroinflammation in the Huntington's disease Midcingulate Cortex.tiff (60.41 MB)
Download fileMolly Ferguson: Mutant Huntingtin Aggregates and Neuroinflammation in the Huntington's disease Midcingulate Cortex
Huntington’s disease (HD) is a genetic neurodegenerative disease which results in mutant huntingtin (mHTT) aggregate formation. These have been linked to neuroinflammation which is primarily mediated by activated microglia. This work shows a potential link between activated microglia and mHTT aggregates in the midcingulate cortex of HD cases.
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