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Andrea Gu: Analyses of whole-genome CRISPR/Cas9 screens identify genetic dependencies in NRAS-mutant melanoma
Melanoma ranks the third most common cancer in New Zealand. Mutations in NRAS are found in approximately 20% of melanoma cases, yet there is no effective treatment specifically for NRAS-mutant melanoma. The identification of genetic dependencies alongside NRAS mutations may provide novel drug targets for the treatment of NRAS-mutant melanoma.
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