HUMBA 12M Protocol 2017.3.21_clean.docx (255.31 kB)
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Healthy Mums and Babies (HUMBA) trial 12 month follow up protocol

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This is the protocol for a follow-up study of 1-year-old children and their mothers from the HUMBA Demonstration Trial, two by two factorial randomised controlled trial of a dietary intervention versus routine dietary advice, and probiotics versus placebo (double blind) in obese pregnant women.

The primary objectives of this study are to determine if at 1 year post expected delivery date whether treatment of obese pregnant women with probiotics versus placebo, and a dietary intervention versus routine dietary advice: 1) For the infant reduces risk factors for later obesity and cardio-metabolic disease, including large body size, rapid growth, excess adiposity, high food avidity (appetite), excess nutrient intake, aortic intima-medial thickening and low physical activity; and improves neurodevelopmental progress; 2) For the mother reduces post-partum weight retention and increases healthy nutritional and physical activity behaviours, and measures of mental health and quality of life.

Funding

Cure Kids Grant 3572

History

Publisher (e.g. University of Auckland)

University of Auckland

Contact email

c.mckinlay@auckland.ac.nz