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Thesis Supplementary Tables

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posted on 2025-07-07, 23:30 authored by Zillah DayshZillah Daysh
<p dir="ltr"><b>Supplementary tables for thesis: Deciphering the genetic mechanisms underlying Alzheimer's Disease</b></p><table><tr><td><p dir="ltr"><b>Supplementary Table 2-1: </b>Hi-C cell lines used to create tissue-specific GRNs</p><p dir="ltr"><b>Supplementary Table 2-2: </b>Two Sample Mendelian Randomisation (2SMR) identifies 179 genes across 9 tissues as causally associated with AD risk</p><p dir="ltr"><b>Supplementary Table 2-3: </b>2SMR identifies KAT8 as the only gene present across 9 tissues as causally associated with AD risk</p><p dir="ltr"><b>Supplementary Table 2-4: </b>Location of SNPs tagging sceQTLs in relation to regulating gene which shows diverging tissue AD risk</p><p dir="ltr"><b>Supplementary Table 3-1:</b><b> </b>Genes included in developmental enrichment analysis based on presence within the Allen Brain Atlas (ABA) RNA-seq datasets</p><p dir="ltr"><b>Supplementary Table 3-2: </b>Cutoff quantile thresholds of Allen Brain Atlas RNA-seq data for gene set enrichment analysis</p><p dir="ltr"><b>Supplementary Table 3-3: </b>Full Multimorbid3D pipeline results</p><p dir="ltr"><b>Supplementary Table 3-4: </b>Multimorbid3D pipeline results of the eight PPINs being investigated</p><p dir="ltr"><b>Supplementary Table 3-5: </b>KAT8:INO80E IBD/SLE PPIN gene set enrichment analysis results within the Allen Brain Atlas dataset</p><p dir="ltr"><b>Supplementary Table 3-6: </b>KAT8:INO80E IBD PPIN gene set enrichment analysis results within the gut dataset</p><p dir="ltr"><b>Supplementary Table 3-7: </b>KAT8:INO80E SLE PPIN gene set enrichment analysis results within the DICE immune cell dataset</p><p dir="ltr"><b>Supplementary Table 3-8: </b>BIN1 T2DM PPIN gene set enrichment analysis results within the Allen Brain Atlas dataset</p><p dir="ltr"><b>Supplementary Table 3-9: </b>KAT8 T2DM PPIN gene set enrichment analysis results within the Allen Brain Atlas dataset</p><p dir="ltr"><b>Supplementary Table 3-10: </b>PLEKHM1 T2DM PPIN gene set enrichment analysis results within the Allen Brain Atlas dataset</p><p dir="ltr"><b>Supplementary Table 3-11: </b>BIN1, KAT8 and PLEKHM1 T2DM PPIN gene set enrichment analysis results within the pancreas dataset</p><p dir="ltr"><b>Supplementary Table 3-12: </b>Depression gene set enrichment analysis results within the Allen Brain Atlas dataset</p></td></tr></table><p></p>

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