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Supplementary data 4. The interaction partners of the NAFLD-candidate genes from the liver-specific PPIN, their pathway enrichment result and the trait enrichment results of the eQTLs regulating them

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posted on 27.11.2021, 11:16 by Sreemol GokuladhasSreemol Gokuladhas
The proteins directly interacting with the proteins encoded by NAFLD-candidate genes were identified from the liver-specific protein-protein interaction network (PPIN). The interacting partners were significantly enriched within biological pathways related to cancers and NAFLD pathogenesis. The eQTLs regulating the interacting partners were enriched for GWAS traits including those that were previously linked to or multimorbid with NAFLD.

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University of Auckland