Supplementary data 2. The gene regulatory interactions of the NAFLD-SNPs within unaffected- and diseased-LGRN
We identified SNPs that are strongly in linkage disequilibrium (r2 >= 0.8) with the NAFLD-associated SNPs reported by GWAS. The gene regulatory interactions of the NAFLD-SNPs (GWAS + LD) were extracted from the LGRN (spatially constrained; derived from a cohort of NAFLD unaffected individuals) and an eQTL-gene network derived from liver samples from a cohort of NAFLD patients (diseased-LGRN).
