Screening plant pathogenic fungi and their natural products for antibacterial activity.

<p>Raw data from screening a variety of fungal plant pathogens from the International Collection of Microbes from Plants (ICMP) for antibacterial data. Fungi screened were <em>Alternaria radicina</em> (ICMP 5619), <em>Cercospora beticola</em> (ICMP 15907), <em>Dactylonectria macrodidyma</em> (ICMP 16789), <em>D. torresensis</em> (ICMP 20542), <em>Ilyonectria europae</em>a (ICMP 16794) <em>and I. liriodendra</em> (ICMP 16795). Fungi were initially screened for activity against bioluminescent derivatives of <em>Acinetobacter baumannii, Pseudomonas aeruginosa, Escherichia coli</em>, <em>Mycobacterium abscessus</em> and <em>M. marinum </em>using an adaptation of the method described in 1. Pure compounds obtained from fungal extracts were tested for activity against <em>M. abscessus</em> and <em>M. marinum</em> as described in 2 & 3. </p> <p><br></p> <p>References:</p> <p>1. Wiles & Grey (2021). Bioluminescence-based 24 well plate assay for screening fungi for activity against <em>Mycobacterium marinum</em>. Protocols.io. DOI:  <a href="https://dx.doi.org/10.17504/protocols.io.bvnbn5an" target="_blank"><strong>dx.doi.org/10.17504/protocols.io.bvnbn5an.</strong></a></p> <p>2. Wiles & Grey (2021). Bioluminescence-based Minimum Inhibitory Concentration (MIC) testing of pure compounds isolated from fungi against <em>Mycobacterium abscessus</em>. Protocols.io. DOI:  <a href="https://dx.doi.org/10.17504/protocols.io.bumcnu2w" target="_blank"><strong>dx.doi.org/10.17504/protocols.io.bumcnu2w</strong></a> </p> <p>3. Wiles & Grey (2021). Bioluminescence-based Minimum Inhibitory Concentration (MIC) testing of pure compounds isolated from fungi against <em>Mycobacterium marinum</em>. Protocols.io. DOI:  <a href="https://dx.doi.org/10.17504/protocols.io.3x7gprn" target="_blank"><strong>dx.doi.org/10.17504/protocols.io.3x7gprn</strong></a> </p> <p>   </p>