sorry, we can't preview this file
...but you can still download left_ventricle_spatial_grn_sig_interactions.txt.gz
left_ventricle_spatial_grn_sig_interactions.txt.gz (31.74 MB)
Left ventricle spatial gene regulatory network
datasetposted on 2022-01-18, 11:07 authored by Roan ZaiedRoan Zaied, Tayaza FadasonTayaza Fadason, Justin O'SullivanJustin O'Sullivan
This dataset consists of spatially constrained eQTLs. Briefly, all common single nucleotide polymorphisms (SNPs; MAF >0.05) present in left ventricle tissue were obtained from GTEx v8 and used to interrogate prepared Hi-C libraries. This allowed for the identification of SNP-gene pairs that are physically interacting. The identified SNP-gene pairs were then tested for eQTL effects by integrating eQTL data from GTEx v8. eQTLs with an adjusted p-value ≤0.05 were selected as being significant (Benjamini-Hochberg).