This metadata record and it's attached files make statements about the kinds of data collected as part of this research, and set out policies for governance of that data, now and in the future.
Description: This trial focused on participants who were of mixed race but who were all pre-diabetic and therefore had a high risk of developing diabetes. As before, the aim was to determine whether or not increased intakes of fructose due to consumption of two kiwifruit per day over a long period could cause harmful metabolic changes in individuals judged by medical criteria as being at high risk of ‘metabolic syndrome’.
The third trial ran for three months – enough time for glycosylated haemoglobin (HbA1c) concentrations in the blood to register increased exposure to glycaemia during the trial period. Several clinical biomarkers were measured, as well as plasma Vitamin C. There were no differences between the kiwifruit and control (water) groups in weight gain, blood lipids, HbA1c and other clinical measures, while plasma Vitamin C increased in the kiwifruit group.
The results showed that kiwifruit, although containing fruit sugars, may be consumed as an excellent source of Vitamin C, by people at risk of diabetes, without unwanted metabolic side effects.
PublisherUniversity of Auckland
Temporal coverage: start2016-01-01
Temporal coverage: end2018-01-01
HVN Project / Programme NameHVN Kiwi, Fruity and Friendly
Data access requirementsNo individual participant data will be available for this trial. Only average values from all participants will be used in the publication.
Principal investigator organisationNew Zealand Institute for Plant and Food Research
Collaborating researchers and affiliationsPrincipal Investigator
Dr John Monro, Principal Scientist, New Zealand Institute for Plant and Food Research, Palmeston North
- Dr Suman Mishra (Plant and Food Research),
- Dr Kerry Bentley-Hewitt (Plant and Food Research)
Data descriptionOutcomes of the Study and associated data
-Glycolsylated haemoglobin level in blood (HbA1c)
-Plasma vitamin C concentration
Associated data: HbA1c, vitamin C
-Serum lipid profile: HDL cholesterol, LDL cholesterol and total lipids
-Plasma uric acid
-Plasma total antioxidant capacity (Superoxide dismutase, LDH activity)
-Biomarkers of inflamnation: C-reactive protein, IL-6, TNF-α
Associated data: HDL cholesterol, LDL cholesterol, total lipids, insulin, glucose, uric acid, antioxidant capacity, biomarkers of inflammation
-Waist circumference, Hip circumference
-7-day diet record
-Self-reported tolerance to intervention
Associated data: height, weight, waist circumference, hip circumference, blood pressure, 7-day diet record, tolerance to intervention
Principal investigator contact email@example.com