posted on 2024-01-17, 01:11authored byJohn Monro, Bernard Venn
<p dir="ltr">This metadata record and it's attached files make statements about the kinds of data collected as part of this research, and set out policies for governance of that data, now and in the future.</p><p dir="ltr"><b>Description: </b>It is important to control the glycaemic and hormonal response to food both for people with normal and impaired glucose tolerance. The purpose of this project was to investigate whether glycaemic and hormonal responses to carbohydrate-containing food can be manipulated by providing meals in two stages (a preload given half an hour before the main meal) compared with meals containing the same amount of carbohydrate given in a single sitting. Our hypothesis was that a beneficial effect of lowering the glycaemic response without adversely affecting the insulin or satiety hormone responses would be observed when a preload containing carbohydrate was given before either breakfast or lunch.</p><p dir="ltr">Healthy New Zealand Chinese participants consumed kiwifruit as part of a carbohydrate meal, in which the kiwifruit carbohydrate partially substituted the primary meal carbohydrate. Total carbohydrate in the meal was held constant yet the kiwifruit was able to significantly reduce the blood glucose response. And if the kiwifruit was consumed about 30 min before the main carbohydrate intake, there was a dramatic reduction in the post-meal blood glucose spike.</p>
No information has been provided regarding individual participant data availability.
Principal investigator organisation
University of Otago
Collaborating researchers and affiliations
Principal Investigators
- Dr Bernard Venn, Department of Human Nutrition, University of Otago, Dunedin
- Dr John Monro, New Zealand Institute for Plant & Food Research Ltd, Palmerston North
Investigators
- Dr Suman Mishra (Plant and Food Research)
- Dr Kerry Bentley-Hewitt (Plant and Food Research)
- Jillian Haszard (University of Otago)
Data description
Outcomes of the Study and associated data
Primary outcomes
-Blood glucose concentration
-Satiety assessed using a visual analogue scale
-Blood vitamin C concentration
Associated data: blood glucose, satiety, blood vitamin C
Secondary outcomes
-Blood insulin concentration
-Blood ghrelin concentration
-Blood glucagon concentration
-Blood glucagon-like peptide-1 (GLP-1) concentration
-Blood interleukin-6 (IL-6) concentration
-Food intake diary
Associated data: insulin, ghrelin, glucagon, GLP-1, IL-6, food intake diary