HVN1924 Metadata Record - Acute effects of green kiwifruit on sleep quality and metabolites of sleep-wake cycles in healthy males
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Description: Sleep is essential for the cellular repair of the body. One night of sleep disturbance can affect a person's ability to concentrate; increasing technical errors and their overall mood the following day. The neurohormone melatonin its precursor serotonin plays a central role in the regulation of sleep-wake. The levels of these neurohormones can be quantified in urine samples by measuring the metabolites of melatonin and serotonin as 6-sulfatoxymelatonin (aMT6s) and 5-hydroxyindoleacetic acid (5-HIAA), respectively. Diet has been shown to impact the levels of these hormones and may have an impact on sleep and mood (Garrido et al., 2010).
Kiwifruit is high in serotonin (Briguglio et al. 2018). The consumption of kiwifruit over one day is shown to increase levels of the 5-HIAA in urine samples. (Feldman & Lee, 1985). Furthermore, sleep quality is improved with the daily consumption of kiwifruit for four weeks (Lin et al. 2011). This project aims to determine the effect of an evening consumption of control, fresh or whole freeze-dried green kiwifruit on urinary metabolites of melatonin, serotonin, and b vitamins as well as subjective sleep quality, and mood in healthy young men.
A randomised controlled, crossover trial is planned. Participants will be given an evening standardised meal and the three intervention to consume with this water, fresh green kiwifruit or dried green kiwifruit powder to consume mixed with water. Upon waking the morning urine sample will be collected, and participants are to complete subjective sleep quality survey and mood survey. Samples and surveys are to be returned to the researcher. After approximately seven days, participants will be asked to consume the next intervention until all three have been consumed.
