The University of Auckland
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HVN1913 Metadata Record - Pasture-raised Advantage: the role of NZ pasture-raised red meat on nutrition, health and wellness in humans. PRotEin Diet SatisfacTION Trial 3 (PREDICTION)

posted on 2024-01-16, 04:02 authored by Andrea BraakhuisAndrea Braakhuis, Emma Bermingham

This metadata record and it's attached files make statements about the kinds of data collected as part of this research, and set out policies for governance of that data, now and in the future.

Description: Protein rich foods that are alternatives to farm-grown meat have received considerable consumer attention. Whilst meat alternatives were once niche food products aimed at vegetarians, they are increasingly marketed to omnivores and "flexitarians", thus contributing to a trend for reductions in red meat intakes. Studies to date have addressed the environmental benefit, plus consumer perceptions and acceptability of meat alternatives, yet there is surprisingly a paucity of data compared the nutritional and digestive differences to meat. The aim of this trial is to compare the digestive consequences of pasture-fed and grain-finished, beef versus a plant-based meat analogue blinded meal.

Healthy, young (20-34 y) participants were asked to consume three separate meals in a crossover, blinded investigation followed by five hours of blood testing and questionnaires to assess the digestive consequences of meat and a plant-based meat analogue. The three meals included either pasture-fed, or grain-finished, or laboratory based protein alternative as a mixed meal, in random order, separated by one week minimum. Plasma samples were assessed for amino acid content, neurotransmitter proteins, chylomicron fatty acid distribution and general health indices.



University of Auckland

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HVN Project / Programme Name


Data access requirements

Individual participant data may be made available on reasonable request. The study protocol will be freely available via publication.

Principal investigator organisation

University of Auckland

Collaborating researchers and affiliations

Principal Investigators: Dr Andrea Braakhuis, Faculty of Medical and Health Sciences, University of Auckland, Auckland Dr Emma Bermingham, Food & Bio-based Products Group, AgResearch Grasslands, Palmerston North Investigators: Professor David Cameron-Smith (Singapore Institute for Clinical Sciences) Toan Pham (University of Auckland) Scott Knowles (AgResearch Grasslands) Matthew Barnett (AgResearch Grasslands) Lovedeep Kaur (Riddet Institute & Massey University)

Data description

Outcomes of the Study and associated data Primary outcome Chylomicron fatty acids in blood (LCPUFA - 18:2 n-6, 18:3 n-3, 20:4 n-6, 20:5 n-3, 22:5 n-3, 22:6 n-3) Associated data: LCPUFA Secondary outcomes - Other chylomicron fatty acid concentrations in blood (14:0, 16:0, 16:1 n-7, 18:0, 18:1 n-9, others) - Amino acids in blood - Neurotransmitters in blood - Glucose / insulin in blood - Minerals / Iron in blood - Inflammatory markers (TNFα, IL-1, IL-6, IL-8, IL-10, IL-13, hs CRP) - Digestive differences based on genetic profile from saliva - Fullness Questionnaire - Digestive Symptoms Questionnaire - Meal Palatability Questionnaire - "Participant insights" from qualitative feedback - Adverse events Associated data: chylomicron fatty acids, amino acids, neurotransmitters, glucose/insulin, minerals/Iron, inflammatory markers, saliva genetic markers, fullness questionnaire, digestive symptoms questionnaire, meal palatability questionnaire, participant insights, adverse events Other outcomes Participant eligibility questionnaire and consent

Principal investigator contact email

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