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Effect of common and experimental anti-tuberculosis treatments on Mycobacterium tuberculosis growing as biofilms.

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posted on 2016-10-27, 10:04 authored by Siouxsie WilesSiouxsie Wiles, James DaltonJames Dalton, Benedict UyBenedict Uy, Brent CoppBrent Copp, Bill DennyBill Denny

Bioluminescence (relative light units [RLU] per well) of M. tuberculosis BSG001 (a stable bioluminescent derivative of H37Rv) growing as pellicles (floating biofilms), 7 days after exposure to different concentrations (Mg/L) of various common and experimental anti-tuberculosis treatments.

Funding

This work was supported by the Maurice Wilkins Centre for Molecular Biodiscovery and the University of Auckland Vice-Chancellor’s Strategic Development Fund and Faculty Research Development Fund. SW was supported by a Sir Charles Hercus Fellowship (09/099

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Publisher (e.g. University of Auckland)

University of Auckland

Contact email

s.wiles@auckland.ac.nz

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Keywords

TB tuberculosis Mycobacteria Mycobacterium tuberculosis biofilm pellicle isoniazid rifampicin pretomanid Medical Bacteriology

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CC BY 4.0

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