Comparison of small molecule inhibitors of poly(ADP)ribose polymerase-1 and DNA-dependent protein kinase as radiosensitizers of head and neck squamous cell carcinoma cell lines
datasetposted on 05.07.2019 by Tet Woo Lee, Way Wong, Benjamin Dickson, Barbara Lipert, Francis Hunter, Michael Hay, William Wilson
Datasets usually provide raw data for analysis. This raw data often comes in spreadsheet form, but can be any collection of data, on which analysis can be performed.
lee_et_al_radiosensitizer_regrowth_data.tsv: Two PARP1 inhibitors (olaparib, veliparib) and two DNA-PK inhibitors (KU57788, IC87361) were tested in 14 HNSCC cell lines, as well as HEK-293 and WI-38/Va-13 cell lines, with drug exposure for 6 or 24 h post-irradiation, using regrowth assays. Full data set including regrowth fractions, total enhancement ratios and sensitizer enhancement ratios, for each cell line, inhibitor concentration, and experiment are in this file.
lee_et_al_analyse_tcga_hnsc_slfn11.zip: Contains R code and required intermediate data for performing analysis of SLFN11 expression in TCGA HNSC cohort.