Phenotype-eGene associations in some multimorbid clusters.
Tayaza Fadason
William Schierding
Thomas Lumley
Justin O'Sullivan
10.17608/k6.auckland.7295702.v3
https://auckland.figshare.com/articles/dataset/Supplementary_Data_3_Phenotype-eGene_associations_in_some_multimorbid_clusters_/7295702
Convex biclustering of shared eGenes among phenotypes resulted in several clusters (Supplementary Figure 4). For each eGene in a cluster, an eGene score (i.e. the percentage of the phenotypes whose associated variants affect the expression of the eGene) is calculated. This data gives for each eGene, the eGene score, number of traits with which the eGene is associated, and its eQTL pairs in the clusters around poly-unsaturated fatty acid metabolism, lung disorders, immune disorders, and mood disorders.<br>
2018-11-07 13:47:06
multimorbidity
fat metabolism
immune disorders
lung disorders
mood disorders
comorbidity
GWAS
pleiotropy
complex disease
eGenes
Hi-C
eQTL
convex biclustering
Medical Genetics (excl. Cancer Genetics)
Quantitative Genetics (incl. Disease and Trait Mapping Genetics)
Genetics